75.3 Synthesis of a Tryptophan-Rich Macrocycle for Inhibiting Protein-Protein Interactions

What:
Student Poster
When:
2:00 PM, Friday 8 Nov 2019 (1 hour 50 minutes)
Where:
Grand Ballroom A/B
Tags:
Natural Sciences & MathematicsExperiential Learning
Discussion:
0

This poster describes the multi-step, organic synthesis of a macrocyle formed when two complementary halves condense to form a 24-member ring.  Both halves comprise trisubstituted triazines.  One half displays two amino acid acetals; the other two protected hydrazines. Deprotection in acid yields the macrocycle.

Participant
Texas Christian University