Author’s Name(s): Perlina Chung, Clare Quigley, Harshika Chawla, Vaisnavy Govindasamy, Elodie Thomas, Yun Wong

Author’s Disclosure Block: Perlina Chung, none; Clare Quigley, none; Harshika Chawla, none; Vaisnavy Govindasamy, none; Elodie Thomas, none; Yun Wong, none

Abstract Body
Purpose:This study compares the rate of recurrence of entropion requiring re-operation after surgical intervention by either lateral tarsal strip with everting sutures (LTS-ES) or lateral wedge resection with transcutaneous retractor plication (LW-TRP). Secondary aims were to investigate other factors which may contribute to recurrence of entropion requiring re-operation.Various surgical procedures have been used to correct vertical and horizontal lid laxities. However, in current literature, it is unclear which procedure has the lower rate of recurrence of entropion. This study compares two methods of combination surgeries correcting both horizontal and vertical lid laxities. Study Design: This was a retrospective cohort study. Methods: Data was collected from digital and physical patient records for patients who underwent entropion correction between January 2018 and January 2020 at James Cook University Hospital, Middlesbrough, United Kingdom.Data analysis was performed using R. Results: A total of 260 entropion operations were included (n= 221 patients). There were 109 males (49.3%) and 112 females (50.7%). There were 201 unoneateral, and 59 bilateral surgeries. The mean age was 77.3 ± 9.2 years. Recurrence occurred in four patients in each group of LW-TRP (4.2%) and LTS-ES (4.2%), with no difference in recurrence rate (p=0.9). Smoking was found to be significantly associated with recurrence of entropion requiring re-operation (p=0.047). When smokers and ex-smokers were included together versus non-smokers, the recurrence of entropion needing re-operation was found to be not significant (p=0.1). Other factors including diabetes mellitus, anticoagulation and antiplatelet medications, previous entropion and cataract surgeries were not found to be statistically significant. Conclusion: There was no difference in the rate of entropion recurrence requiring reoperation between LTS-ES and LW-TRP. An association was found between smoking status with recurrence requiring reoperation after surgical repair. With smoking cessation, this association appeared to be reversible.