Alien Disabilities

We all have a rough idea of what constitutes disability in our human world, specifically in American culture. What would be a severe disability to an alien but not to us? Where losing a sense of smell might be somewhat limiting to humans, how would that affect a being in a civilization of dogs-creatures? What about an intelligent plant-creature with no roots? What if everyone but you had the ability to jack into an immersive virtual cyberpunk world? What alien or "future" disabilities have already been written about? And thinking along these lines, how do assumptions about ability in our own world shape what is and is not considered disability now? Come for a respectful discussion of disabilities in imaginative worlds.